Reflexin A, a new indole alkaloid from Rauvolfia reflexa induces apoptosis against colon cancer cells

antineoplastic agent; caspase 3; caspase 7; caspase 8; caspase 9; indole alkaloid; macusine; Rauvolfia reflexa extract; Rauwolfia extract; reflexin A; unclassified drug; vinorine; flavanone derivative; indole alkaloid; reflexin; acute toxicity; antineoplastic activity; apoptosis; Article; bark; cell...

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Bibliographic Details
Main Authors: Fadaeinasab M., Karimian H., Omar H., Taha H., khorasani A., Banisalam B., Aziz Ketuly K., Abdullah Z.
Other Authors: 55662460000
Format: Article
Published: Taylor and Francis Ltd. 2023
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Institution: Universiti Tenaga Nasional
Description
Summary:antineoplastic agent; caspase 3; caspase 7; caspase 8; caspase 9; indole alkaloid; macusine; Rauvolfia reflexa extract; Rauwolfia extract; reflexin A; unclassified drug; vinorine; flavanone derivative; indole alkaloid; reflexin; acute toxicity; antineoplastic activity; apoptosis; Article; bark; cell invasion; cell migration; cell proliferation; colon cancer; controlled study; drug isolation; drug safety; drug structure; enzyme activation; G1 phase cell cycle checkpoint; HCT 116 cell line; human; human cell; IC50; Rauvolfia reflexa; Rauwolfia; apoptosis; chemical structure; colon tumor; Apoptosis; Colonic Neoplasms; Flavanones; Humans; Indole Alkaloids; Molecular Structure; Rauwolfia