Analysis of Insulin Sensitivity Stochastic Models between STAR Original and Malaysian Cohorts

Decision support systems; Glucose; Hospital data processing; Intensive care units; Physiological models; Stars; Stochastic control systems; Stochastic models; Stochastic systems; Clinical variable; Control of physiological; Control protocols; Decision supports; Glycemic control; Insulin sensitivity;...

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Main Authors: Wai Lee J.W., Chiew Y.S., Tan C.P., Razak A.A., Abdul Razak N.N.
Other Authors: 57349841700
Format: Conference Paper
Published: Elsevier B.V. 2023
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Institution: Universiti Tenaga Nasional
id my.uniten.dspace-25617
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spelling my.uniten.dspace-256172023-05-29T16:11:46Z Analysis of Insulin Sensitivity Stochastic Models between STAR Original and Malaysian Cohorts Wai Lee J.W. Chiew Y.S. Tan C.P. Razak A.A. Abdul Razak N.N. 57349841700 57191987083 35086948100 56960052400 37059587300 Decision support systems; Glucose; Hospital data processing; Intensive care units; Physiological models; Stars; Stochastic control systems; Stochastic models; Stochastic systems; Clinical variable; Control of physiological; Control protocols; Decision supports; Glycemic control; Insulin sensitivity; Malaysians; Model-based OPC; Stochastic control; Stochastic-modeling; Insulin Maintaining healthy blood glucose (BG) levels is vital in ensuring the health of intensive care unit patients. In present work, there exists model-based glycemic control protocols that capture insulin-glucose dynamics that can provide patient-specific treatments. The Stochastic Targeted Glycemic Control (STAR) protocol is a model-based glycemic control protocol that utilizes stochastic modelling together with the Intensive Control Insulin Glycemic Control (ICING) model. STAR has shown its effectiveness in Christchurch and Hungary. However, it is currently less effective in Malaysia. A study is conducted to compare the stochastic model between the STAR original and Malaysian cohort to identify if the difference in effectiveness is due to a difference in stochastic insulin sensitivity (SI) models between cohorts. Results from this study show that there could be a difference of up to 49.4% in predictive ability of the stochastic models from the two cohorts, suggesting that it could play a role in being the cause for its lack in effectiveness. With further patient data collection, this hypothesis could be proven or otherwise eliminated from the possible causes for the lack of effectiveness of the STAR protocol in Malaysia. � 2020 Elsevier B.V.. All rights reserved. Final 2023-05-29T08:11:46Z 2023-05-29T08:11:46Z 2020 Conference Paper 10.1016/j.ifacol.2020.12.436 2-s2.0-85119627760 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119627760&doi=10.1016%2fj.ifacol.2020.12.436&partnerID=40&md5=7619e9125880566bad15c56aaaf8f573 https://irepository.uniten.edu.my/handle/123456789/25617 53 2 16143 16148 All Open Access, Bronze Elsevier B.V. Scopus
institution Universiti Tenaga Nasional
building UNITEN Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Tenaga Nasional
content_source UNITEN Institutional Repository
url_provider http://dspace.uniten.edu.my/
description Decision support systems; Glucose; Hospital data processing; Intensive care units; Physiological models; Stars; Stochastic control systems; Stochastic models; Stochastic systems; Clinical variable; Control of physiological; Control protocols; Decision supports; Glycemic control; Insulin sensitivity; Malaysians; Model-based OPC; Stochastic control; Stochastic-modeling; Insulin
author2 57349841700
author_facet 57349841700
Wai Lee J.W.
Chiew Y.S.
Tan C.P.
Razak A.A.
Abdul Razak N.N.
format Conference Paper
author Wai Lee J.W.
Chiew Y.S.
Tan C.P.
Razak A.A.
Abdul Razak N.N.
spellingShingle Wai Lee J.W.
Chiew Y.S.
Tan C.P.
Razak A.A.
Abdul Razak N.N.
Analysis of Insulin Sensitivity Stochastic Models between STAR Original and Malaysian Cohorts
author_sort Wai Lee J.W.
title Analysis of Insulin Sensitivity Stochastic Models between STAR Original and Malaysian Cohorts
title_short Analysis of Insulin Sensitivity Stochastic Models between STAR Original and Malaysian Cohorts
title_full Analysis of Insulin Sensitivity Stochastic Models between STAR Original and Malaysian Cohorts
title_fullStr Analysis of Insulin Sensitivity Stochastic Models between STAR Original and Malaysian Cohorts
title_full_unstemmed Analysis of Insulin Sensitivity Stochastic Models between STAR Original and Malaysian Cohorts
title_sort analysis of insulin sensitivity stochastic models between star original and malaysian cohorts
publisher Elsevier B.V.
publishDate 2023
_version_ 1806428231929167872