Development of graphene based nanocomposites towards medical and biological applications
Biocompatibility; Chemical vapor deposition; Controlled drug delivery; Nanocomposites; Quality control; Targeted drug delivery; Biological applications; Camptothecin (CPT); Chemical vapour deposition; Cytotoxic effects; Drug delivery applications; Functionalisation; Graphene nanocomposites; High spe...
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2023
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my.uniten.dspace-256712023-05-29T16:12:31Z Development of graphene based nanocomposites towards medical and biological applications Mousavi S.M. Low F.W. Hashemi S.A. Lai C.W. Ghasemi Y. Soroshnia S. Savardashtaki A. Babapoor A. Pynadathu Rumjit N. Goh S.M. Amin N. Tiong S.K. 57217768274 56513524700 57201310181 54879860000 6506711864 57208784235 57057868900 36501392200 57191580733 25521891600 7102424614 15128307800 Biocompatibility; Chemical vapor deposition; Controlled drug delivery; Nanocomposites; Quality control; Targeted drug delivery; Biological applications; Camptothecin (CPT); Chemical vapour deposition; Cytotoxic effects; Drug delivery applications; Functionalisation; Graphene nanocomposites; High specific surface area; Graphene; antiinfective agent; camptothecin; doxorubicin; firtecan; graphene; graphene oxide; nanocomposite; polymer; graphite; nanocomposite; biocompatibility; bioimaging; chemexfoliation; chemical procedures; chemical vapor deposition; cytotoxicity; diagnosis; drug delivery system; epitaxy; HCT 116 cell line; human; imaging; in vitro study; nonhuman; reduction (chemistry); regenerative medicine; Review; synthesis; tissue engineering; animal; chemistry; nanomedicine; procedures; Animals; Graphite; Humans; Nanocomposites; Nanomedicine Graphene and its derivative materials present high potential towards medical and biological applications, including drug delivery and bioimaging, due to their exceptional properties such as thermal conductivity and high specific surface area. The main focus of this work is to review the current development of graphene materials and the derivatives for biocompatible, bioimaging and drug delivery applications. Also, the synthesis methods with variation of graphene nanocomposites and the functionalisation will be further explained. For the graphene approaches, chemical vapour deposition (CVD) is the best-known technique to make high-quality graphene sheet by growth route with mass production. By considering the organic graphene nanocomposites, the biocompatibility and cytotoxic effects against graphene nanocomposites were evaluated for biomedical employments such as high quality bioimaging and effective drug delivery for cancer treatments. For example, graphene oxide incorporated with PEG and loaded with SN 38 for camptothecin analolgue as anticancer drug and revealed high cytotoxicity has an effect of 1000 times better effect than CPT in HCT-116 cells. Their drug delivery ability for both in-vivo and in-vitro applications compared to the controlled drugs such as doxorubicin (DOX) will be discussed accordingly. The graphene and its deriavatives possess some intriguing properties, which will lead to drug delivery due to strong biocompatibility and cyctotoxic effect towards biomedicine applications. � 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Final 2023-05-29T08:12:31Z 2023-05-29T08:12:31Z 2020 Review 10.1080/21691401.2020.1817052 2-s2.0-85091054171 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85091054171&doi=10.1080%2f21691401.2020.1817052&partnerID=40&md5=c4fa4ad5cefbfebf705b4215a1e536db https://irepository.uniten.edu.my/handle/123456789/25671 48 1 1189 1205 All Open Access, Gold Taylor and Francis Ltd. Scopus |
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Biocompatibility; Chemical vapor deposition; Controlled drug delivery; Nanocomposites; Quality control; Targeted drug delivery; Biological applications; Camptothecin (CPT); Chemical vapour deposition; Cytotoxic effects; Drug delivery applications; Functionalisation; Graphene nanocomposites; High specific surface area; Graphene; antiinfective agent; camptothecin; doxorubicin; firtecan; graphene; graphene oxide; nanocomposite; polymer; graphite; nanocomposite; biocompatibility; bioimaging; chemexfoliation; chemical procedures; chemical vapor deposition; cytotoxicity; diagnosis; drug delivery system; epitaxy; HCT 116 cell line; human; imaging; in vitro study; nonhuman; reduction (chemistry); regenerative medicine; Review; synthesis; tissue engineering; animal; chemistry; nanomedicine; procedures; Animals; Graphite; Humans; Nanocomposites; Nanomedicine |
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57217768274 Mousavi S.M. Low F.W. Hashemi S.A. Lai C.W. Ghasemi Y. Soroshnia S. Savardashtaki A. Babapoor A. Pynadathu Rumjit N. Goh S.M. Amin N. Tiong S.K. |
| format |
Review |
| author |
Mousavi S.M. Low F.W. Hashemi S.A. Lai C.W. Ghasemi Y. Soroshnia S. Savardashtaki A. Babapoor A. Pynadathu Rumjit N. Goh S.M. Amin N. Tiong S.K. |
| spellingShingle |
Mousavi S.M. Low F.W. Hashemi S.A. Lai C.W. Ghasemi Y. Soroshnia S. Savardashtaki A. Babapoor A. Pynadathu Rumjit N. Goh S.M. Amin N. Tiong S.K. Development of graphene based nanocomposites towards medical and biological applications |
| author_sort |
Mousavi S.M. |
| title |
Development of graphene based nanocomposites towards medical and biological applications |
| title_short |
Development of graphene based nanocomposites towards medical and biological applications |
| title_full |
Development of graphene based nanocomposites towards medical and biological applications |
| title_fullStr |
Development of graphene based nanocomposites towards medical and biological applications |
| title_full_unstemmed |
Development of graphene based nanocomposites towards medical and biological applications |
| title_sort |
development of graphene based nanocomposites towards medical and biological applications |
| publisher |
Taylor and Francis Ltd. |
| publishDate |
2023 |
| _version_ |
1806425701933383680 |