A Strategy toward the Biomimetic Synthesis of (±)-Morusalbanol A Pentamethyl Ether

• Main Authors: Tee, J.T., Keane, T., Meijer, A.J.H.M., Khaledi, H., Rahman, N.A., Chee, C.F.
• Format: Article
• Language: English
• Published: 2017
• Subjects: Biomimetics; Carbon; Cyclization
• Institution: Universiti Tenaga Nasional

A strategy toward the biomimetic synthesis of morusalbanol A pentamethyl ether is described. The synthesis is based on a hydrogen-bond-assisted Diels-Alder cycloaddition between a dehydroprenyl diene and a chalcone dienophile. Selective cleavage of the ortho-methyl ether of the resulting cycloadduct...