Scalable production of recombinant membrane active peptides and its potential as a complementary adjunct to conventional chemotherapeutics

• Main Authors: Rothan, H.A., Ambikabothy, J., Abdulrahman, A.Y., Bahrani, H., Golpich, M., Amini, E., Rahman, N.A., Teoh, T.C., Mohamed, Z., Yusof, R.
• Format: Article
• Language: English
• Published: 2017
• Institution: Universiti Tenaga Nasional

The production of short anticancer peptides in recombinant form is an alternative method for costly chemical manufacturing. However, the limitations of host toxicity, bioactivity and column purification have impaired production in mass quantities. In this study, short cationic peptides were produced...