A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity

• Main Authors: Ikram, N.K.K., Durrant, J.D., Muchtaridi, M., Zalaludin, A.S., Purwitasari, N., Mohamed, N., Rahim, A.S.A., Lam, C.K., Normi, Y.M., Rahman, N.A., Amaro, R.E., Wahab, H.A.
• Format: Article
• Language: English
• Published: 2017
• Institution: Universiti Tenaga Nasional

Recent outbreaks of highly pathogenic and occasional drug-resistant influenza strains have highlighted the need to develop novel anti-influenza therapeutics. Here, we report computational and experimental efforts to identify influenza neuraminidase inhibitors from among the 3000 natural compounds in...