Formation of 1,3,4-oxadiazolines and 1,3,4-oxadiazepines through acetylation of salicylic hydrazones
A new series of 1,3,4-oxadiazolines and 1,3,4-oxadiazepines are prepared in a one-step reaction through cyclization of various N-benzylidene-2-hydroxybenzohydrazides. Cyclization in acetic anhydride yielded 1,3,4-oxadiazolines, while the reaction carried out in acetic anhydride-acetic acid gave 1,3,...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2017
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| Institution: | Universiti Tenaga Nasional |
| Language: | English |
| Summary: | A new series of 1,3,4-oxadiazolines and 1,3,4-oxadiazepines are prepared in a one-step reaction through cyclization of various N-benzylidene-2-hydroxybenzohydrazides. Cyclization in acetic anhydride yielded 1,3,4-oxadiazolines, while the reaction carried out in acetic anhydride-acetic acid gave 1,3,4-oxadiazepines, in some cases. © 2014 Elsevier Ltd. All rights reserved. |
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