Fractional view analysis of sexual transmitted human papilloma virus infection for public health

• Main Authors: Bahi M.C., Bahramand S., Jan R., Boulaaras S., Ahmad H., Guefaifia R.
• Other Authors: 57194858779
• Format: Article
• Published: Nature Research 2025
• Subjects: Cost of Illness; Human Papillomavirus Viruses; Humans; Papillomavirus Infections; Public Health; Sexual Behavior; cost of illness; human; papillomavirus infection; public health; sexual behavior; Wart virus
• Institution: Universiti Tenaga Nasional

The infection of human papilloma virus (HPV) poses a global public health challenge, particularly in regions with limited access to health care and preventive measures, contributing to health disparities and increased disease burden. In this research work, we present a new model to explore the transmission dynamics of HPV infection, incorporating the impact of vaccination through the Atangana?Baleanu derivative. We establish the positivity and uniqueness of the solution for the proposed model HPV infection. The threshold parameter is determined through the next-generation matrix method, symbolized by R0. Moreover, we investigate the local asymptotic stability of the infection-free steady-state of the system. The existence of the solutions of the recommended model is determined through fixed-point theory. A numerical scheme is presented to visualize the dynamical behavior of the system with variation of input factors. We have shown the impact of input parameters on the dynamics of the system through numerical simulations. The findings of our investigation delineated the principal parameters exerting significant influence for the control and prevention of HPV infection. ? The Author(s) 2024.