Benzimidazole derivatives as potential dual inhibitors for PARP-1 and DHODH
Poly (ADP-ribose) polymerases (PARPs) play diverse roles in various cellular processes that involve DNA repair and programmed cell death. Amongst these polymerases is PARP-1 which is the key DNA damage-sensing enzyme that acts as an initiator for the DNA repair mechanism. Dihydroorotate dehydrogenas...
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Main Authors: | , , , , , , , , , , , |
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2018
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Online Access: | http://dspace.uniten.edu.my/jspui/handle/123456789/9736 |
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Institution: | Universiti Tenaga Nasional |