Hybrid nanoparticulate system of Fluvastatin loaded phospholipid, alpha lipoic acid and melittin for the management of colon cancer

As a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, Fluvastatin (FLV) is used for reducing low-density lipoprotein (LDL) cholesterol as well as to prevent cardiovascular problems. FLV showed cell line cytotoxicity and antitumor effect. Melittin (MEL) exhibits antineoplastic activity...

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Bibliographic Details
Main Authors: Alfaleh, Mohamed A., Fahmy, Omar, Abourehab, Mohammed A. S., Fahmy, Usama A., Alharbi, Awaad S., Alhakamy, Nabil A.
Format: Article
Published: Nature Publishing Group 2022
Online Access:http://psasir.upm.edu.my/id/eprint/101752/
https://www.nature.com/articles/s41598-022-24151-3
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Institution: Universiti Putra Malaysia