Dietary exposure to acrylamide among the Malaysian adult population

This study aimed to estimate the Malaysian adult population's current dietary exposure and margin of exposure (MOE) to the carcinogenic processing contaminant, acrylamide. A total of 448 samples from 11 types of processed foods were collected randomly throughout Malaysia in the year 2015 and 20...

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Main Authors: Nur Hidayah, Jamaludin, Abdul Razis, Ahmad Faizal, Jambari, Nuzul Noorahya, Chai, Lay Ching, You, Lijun, Sanny, Maimunah
Format: Article
Published: Elsevier 2024
Online Access:http://psasir.upm.edu.my/id/eprint/106156/
https://www.sciencedirect.com/science/article/abs/pii/S0278691524000681
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Institution: Universiti Putra Malaysia
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spelling my.upm.eprints.1061562024-09-03T07:54:20Z http://psasir.upm.edu.my/id/eprint/106156/ Dietary exposure to acrylamide among the Malaysian adult population Nur Hidayah, Jamaludin Abdul Razis, Ahmad Faizal Jambari, Nuzul Noorahya Chai, Lay Ching You, Lijun Sanny, Maimunah This study aimed to estimate the Malaysian adult population's current dietary exposure and margin of exposure (MOE) to the carcinogenic processing contaminant, acrylamide. A total of 448 samples from 11 types of processed foods were collected randomly throughout Malaysia in the year 2015 and 2016. Acrylamide was analysed in samples using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) with a limit of detection (LOD) of 10 μg/kg and a limit of quantification (LOQ) of 25 μg/kg. The highest average level of acrylamide (772 ± 752 μg/kg) was found in potato crisps, followed by French fries (415 ± 914 μg/kg) and biscuits (245 ± 195 μg/kg). The total acrylamide exposure for the adult Malaysian was 0.229 and 1.77 μg/kg body weight per day for average and high consumers, respectively. The MOE were 741 and 1875 for the average consumer based on cancer and non-cancer effects of acrylamide, respectively. Meanwhile, for high consumers, the MOE is 96 for cancer and 243 for non-cancer effects. These findings indicate potential carcinogenic risks from acrylamide exposure among Malaysian adults, especially in Malay and other Bumiputra groups compared to Chinese, Indian, and other ethnic groups, while non-cancer effects appeared less concerning. Elsevier 2024-03 Article PeerReviewed Nur Hidayah, Jamaludin and Abdul Razis, Ahmad Faizal and Jambari, Nuzul Noorahya and Chai, Lay Ching and You, Lijun and Sanny, Maimunah (2024) Dietary exposure to acrylamide among the Malaysian adult population. Food and Chemical Toxicology, 185. art. no. 114502. ISSN 0278-6915; ESSN: 1873-6351 https://www.sciencedirect.com/science/article/abs/pii/S0278691524000681
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description This study aimed to estimate the Malaysian adult population's current dietary exposure and margin of exposure (MOE) to the carcinogenic processing contaminant, acrylamide. A total of 448 samples from 11 types of processed foods were collected randomly throughout Malaysia in the year 2015 and 2016. Acrylamide was analysed in samples using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) with a limit of detection (LOD) of 10 μg/kg and a limit of quantification (LOQ) of 25 μg/kg. The highest average level of acrylamide (772 ± 752 μg/kg) was found in potato crisps, followed by French fries (415 ± 914 μg/kg) and biscuits (245 ± 195 μg/kg). The total acrylamide exposure for the adult Malaysian was 0.229 and 1.77 μg/kg body weight per day for average and high consumers, respectively. The MOE were 741 and 1875 for the average consumer based on cancer and non-cancer effects of acrylamide, respectively. Meanwhile, for high consumers, the MOE is 96 for cancer and 243 for non-cancer effects. These findings indicate potential carcinogenic risks from acrylamide exposure among Malaysian adults, especially in Malay and other Bumiputra groups compared to Chinese, Indian, and other ethnic groups, while non-cancer effects appeared less concerning.
format Article
author Nur Hidayah, Jamaludin
Abdul Razis, Ahmad Faizal
Jambari, Nuzul Noorahya
Chai, Lay Ching
You, Lijun
Sanny, Maimunah
spellingShingle Nur Hidayah, Jamaludin
Abdul Razis, Ahmad Faizal
Jambari, Nuzul Noorahya
Chai, Lay Ching
You, Lijun
Sanny, Maimunah
Dietary exposure to acrylamide among the Malaysian adult population
author_facet Nur Hidayah, Jamaludin
Abdul Razis, Ahmad Faizal
Jambari, Nuzul Noorahya
Chai, Lay Ching
You, Lijun
Sanny, Maimunah
author_sort Nur Hidayah, Jamaludin
title Dietary exposure to acrylamide among the Malaysian adult population
title_short Dietary exposure to acrylamide among the Malaysian adult population
title_full Dietary exposure to acrylamide among the Malaysian adult population
title_fullStr Dietary exposure to acrylamide among the Malaysian adult population
title_full_unstemmed Dietary exposure to acrylamide among the Malaysian adult population
title_sort dietary exposure to acrylamide among the malaysian adult population
publisher Elsevier
publishDate 2024
url http://psasir.upm.edu.my/id/eprint/106156/
https://www.sciencedirect.com/science/article/abs/pii/S0278691524000681
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