HIF-1 activation and inflammatory responses to hypoxiahypoxia

• Main Authors: Shaharuddin, Shazreen, Nik Abd Rahman, Nik Mohd Afizan, Masarudin, Mas Jaffri, Alamassi, Mohammedarfat N
• Format: Article
• Published: Embry-Riddle Aeronautical University 2023
• Online Access: http://psasir.upm.edu.my/id/eprint/108172/; https://commons.erau.edu/ijaaa/vol10/iss2/3/
• Institution: Universiti Putra Malaysia

Acute hypoxia is a significant physiological danger during high-altitude flying and military aircraft missions. The human brain requires a constant supply of oxygen to function properly, and is susceptible to settings with low availability of air oxygen. Hypoxia can influence inflammatory signalling...