Increased radical scavenging activity of thymoquinone and L-ascorbic acid dual encapsulated in palmitoyl-chitosan nanoparticles in a human normal lung fibroblast, MRC-5 due to synergistic antioxidative effects

• Main Authors: Othman, Nurhanisah, Md. Jamil, Siti Nurul Ain, Masarudin, Mas Jaffri, Mohd Jusoh, Ruqayyah Ainul Bashirah, Alamassi, Mohammed Numan
• Format: Article
• Published: Royal Society of Chemistry 2023
• Online Access: http://psasir.upm.edu.my/id/eprint/109138/; https://pubs.rsc.org/en/content/articlelanding/2023/ra/d3ra04326f
• Institution: Universiti Putra Malaysia

Less effective antioxidant supplementation in combating free radicals is often related to the lack of the formulation of carriers. The antioxidant may be one of the most powerful substances but is marred by poor uptake by cells when the carrier degraded and dissolved too rapidly. Nanoparticle (NP)...