Synthesis of diarylpentadienones and pyrazoline derivatives as potential α-glucosidase inhibitor and their antioxidant activities

• Main Authors: Adam, Faruk Auwal, Md Razali, Mohammad Aidiel, Rukayardi, Yaya, Mastuki, Siti Nurulhuda, Wei, Leong Sze, Mad Nasir, Nadiah, Mohd Faudzi, Siti Munirah
• Format: Article
• Published: Malaysian Institute of Chemistry 2023
• Online Access: http://psasir.upm.edu.my/id/eprint/109339/; https://ikm.org.my/publications/malaysian-journal-of-chemistry/view-abstract.php?abs=J0043-cc1b612
• Institution: Universiti Putra Malaysia

Diabetes mellitus type II (T2DM) is a global public health crisis that can lead to death and disability if poorly treated. T2DM patients are usually prescribed antidiabetic drugs, including α-glucosidase inhibitors (AGIs), but their use can lead to complications. Epidemiological studies have already...