Non-invasive prenatal testing (NIPT): reliability, challenges, and future directions

• Main Authors: Jayashankar, Siva Shantini, Nasaruddin, Muhammad Luqman, Hassan, Muhammad Faiz, Dasrilsyah, Rima Anggrena, Shafiee, Mohamad Nasir, Ismail, Noor Akmal Shareela, Alias, Ekram
• Format: Article
• Published: Multidisciplinary Digital Publishing Institute 2023
• Online Access: http://psasir.upm.edu.my/id/eprint/110169/; https://www.mdpi.com/2075-4418/13/15/2570
• Institution: Universiti Putra Malaysia

Non-invasive prenatal testing was first discovered in 1988; it was primarily thought to be able to detect common aneuploidies, such as Patau syndrome (T13), Edward Syndrome (T18), and Down syndrome (T21). It comprises a simple technique involving the analysis of cell-free foetal DNA (cffDNA) obtaine...