Optimization of ionic liquid-based aqueous two-phase system for partial purification of bacteriocin-like inhibitory substance from Enterococcus faecium CC2 and its inhibitory activity against Streptococcus mutans

• Main Authors: Ng, Zhang Jin, Ng, Hui Suan, Kee, Phei Er, Gan, Chee-Yuen, Ahmad Mokhtar, Ana Masara, Abu Zarin, Mazni, Lee, Chee Keong, Tan, Joo Shun, Lan, John Chi-Wei
• Format: Article
• Language: English
• Published: Elsevier 2024
• Online Access: http://psasir.upm.edu.my/id/eprint/111337/1/1-s2.0-S1876107024000063-main.pdf; http://psasir.upm.edu.my/id/eprint/111337/; https://linkinghub.elsevier.com/retrieve/pii/S1876107024000063
• Institution: Universiti Putra Malaysia

Background: Bacteriocin-like inhibitory substance (BLIS) demonstrates potent inhibitory effect against oral pathogens. To apply in oral care products, high purity of BLIS is required in view of the safety and effectiveness in the application. Therefore, aqueous two-phase systems (ATPS) are introduce...