Novel inhaled andrographolide for treatment of lung cancer: in vitro assessment

• Main Authors: Masarudin, Mas Jaffri, Jothi. N, Arul, Mohtar, Noratiqah, Parumasivam, Thaigarajan
• Format: Article
• Language: English
• Published: Elsevier Ltd 2024
• Online Access: http://psasir.upm.edu.my/id/eprint/111592/1/PIIS2405844024067926.pdf; http://psasir.upm.edu.my/id/eprint/111592/; https://www.sciencedirect.com/science/article/pii/S2405844024067926
• Institution: Universiti Putra Malaysia

Andrographolide is a plant-based compound that showed promising activity against lung cancer. However, the compound's poor water solubility and low bioavailability limit its oral administration. Inhaled drug delivery of andrographolide is highly favourable as it delivers active ingredients dire...