Oral and topical administration of a geranyl acetophenone attenuates DNCB‑induced atopic dermatitis‑like skin lesions in BALB/c mice

• Main Authors: Mohd Kasim, Vivi Nur Khalieda, Lee, Yu Zhao, Bakrin, Ikmal Hisyam, Hussain, Mohd Khairi, Ahmad Israf, Daud, Shaari, Khozirah, Tan, Ji Wei, Lee, Ming Tatt, Tham, Chau Ling
• Format: Article
• Language: English
• Published: Nature Research 2024
• Online Access: http://psasir.upm.edu.my/id/eprint/112239/1/tHGA%20on%20DNCB%20Induced%20Atopic%20Deramatitis.pdf; http://psasir.upm.edu.my/id/eprint/112239/; https://www.nature.com/articles/s41598-024-66601-0
• Institution: Universiti Putra Malaysia

Atopic dermatitis (AD) is a chronic, allergic inflammatory skin disorder that lacks a definite cure. Using a mouse DNCB-induced AD-like skin lesions model, this study evaluated the potential therapeutic utility of tHGA as an oral and topical treatment for AD. Male BALB/c mice were sensitised and cha...