Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep

Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep

The protective effect of phenobarbitone and griseofulvin against signal grass (B. decumbens) toxicity were studied in fifty-three Wiltshire x Malin (Indigenous Malaysian) male sheep. Twenty-six animals were used in phenobarbitone experiment and twenty-seven animals were used in griseofulvin exper...

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Main Author: Ab. Hamid, Hasiah
Format: Thesis
Language:English
English
Published: 2001
Online Access:http://psasir.upm.edu.my/id/eprint/11224/1/FPSK_M_2001_11.pdf
http://psasir.upm.edu.my/id/eprint/11224/
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Institution: Universiti Putra Malaysia
Language: English
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id my.upm.eprints.11224
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spelling my.upm.eprints.112242024-06-12T08:34:30Z http://psasir.upm.edu.my/id/eprint/11224/ Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep Ab. Hamid, Hasiah The protective effect of phenobarbitone and griseofulvin against signal grass (B. decumbens) toxicity were studied in fifty-three Wiltshire x Malin (Indigenous Malaysian) male sheep. Twenty-six animals were used in phenobarbitone experiment and twenty-seven animals were used in griseofulvin experiment. Grazing on signal grass significantly decreased the concentration of cytochrome P-4S0 and the activity of drug metabolizing enzyme, viz. aminopyrine-N-demethylase, aniline-4- hydroxylase, UDP-glucuronyltransferase and glutathione-S-transferase in liver and kidney of sheep. The concentration of cytochrome P-4S0 was determined in microsomal fraction according to the method of Omura and Sato (1964a) as described by Mazel (1971). The activities of aminopyrine-N-demethylase and aniline-4- hydroxylase were determined using Mazel, 1971 method by estimating the 2001-02 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/11224/1/FPSK_M_2001_11.pdf Ab. Hamid, Hasiah (2001) Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep. Masters thesis, Universiti Putra Malaysia. English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
description The protective effect of phenobarbitone and griseofulvin against signal grass (B. decumbens) toxicity were studied in fifty-three Wiltshire x Malin (Indigenous Malaysian) male sheep. Twenty-six animals were used in phenobarbitone experiment and twenty-seven animals were used in griseofulvin experiment. Grazing on signal grass significantly decreased the concentration of cytochrome P-4S0 and the activity of drug metabolizing enzyme, viz. aminopyrine-N-demethylase, aniline-4- hydroxylase, UDP-glucuronyltransferase and glutathione-S-transferase in liver and kidney of sheep. The concentration of cytochrome P-4S0 was determined in microsomal fraction according to the method of Omura and Sato (1964a) as described by Mazel (1971). The activities of aminopyrine-N-demethylase and aniline-4- hydroxylase were determined using Mazel, 1971 method by estimating the
format Thesis
author Ab. Hamid, Hasiah
spellingShingle Ab. Hamid, Hasiah
Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep
author_facet Ab. Hamid, Hasiah
author_sort Ab. Hamid, Hasiah
title Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep
title_short Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep
title_full Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep
title_fullStr Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep
title_full_unstemmed Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep
title_sort protective effect of phenorbarbitone and griseofulvin againt signal grass (brachiaria decumbens)toxiciti in sheep
publishDate 2001
url http://psasir.upm.edu.my/id/eprint/11224/1/FPSK_M_2001_11.pdf
http://psasir.upm.edu.my/id/eprint/11224/
_version_ 1802978768027910144

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