Antifungal activity of synthetic xanthenone against fluconazole-resistant Candida auris and its mechanism of action

• Main Authors: Ramli, Amirah Hani, Jayathilaka, E.H.T. Thulshan, Dias, Mawalle Kankanamge Hashita Madhawa, Abdul Malek, Emilia, Jain, Neha, An, Jongkeol, Churchill, David G., Rukayadi, Yaya, Swain, Puspanjali, Kim, Cheol-Hee, de Zoysa, Mahanama, Mohd Faudzi, Siti Munirah
• Format: Article
• Language: English
• Published: Academic Press 2024
• Online Access: http://psasir.upm.edu.my/id/eprint/113308/1/113308.pdf; http://psasir.upm.edu.my/id/eprint/113308/; https://www.sciencedirect.com/science/article/pii/S088240102400264X?via%3Dihub
• Institution: Universiti Putra Malaysia

Candida auris, an emerging multidrug-resistant fungal pathogen discovered in Japan in 2009, poses a significant global health threat, with infections reported in about 25 countries. The escalation of drug-resistant strains underscores the urgent need for new treatment options. This study aimed to in...