Brown fat uptake of 18F-FDG on dual time point PET/CT imaging.

• Main Authors: Abdul Razak , Hairil Rashmizal, Abdul Rahim, Noraini, Rossetti, Claudio, Nordin, Abdul Jalil
• Format: Article
• Language: English
• Published: Singapore Medical Association 2010
• Online Access: http://psasir.upm.edu.my/id/eprint/13459/1/Brown%20fat%20uptake%20of%2018F.pdf; http://psasir.upm.edu.my/id/eprint/13459/
• Institution: Universiti Putra Malaysia

The aim of this report was to assess the changes in the 18F-fluorodeoxyglucose (18F-FDG) uptake of brown fats on integrated positron emission tomography/computed tomography (PET/ CT) imaging. The patient presented with an enlargement of the neck lymph nodes, and was suspicious for tuberculous lymphadenitis. A whole body PET/CT imaging was performed, followed by a delayed imaging of the neck and thoracic regions. A visually increased 18F-FDG uptake was taken as a positive finding. A semi-quantitative evaluation was performed using a maximum standardised uptake value (SUVmax) with a cut-off value above 2.5. There were a number of 18F-FDG avid activity areas seen at the supraclavicular, mediastinal, paravertebral and perirenal regions. These are in keeping with the physiological 18F-FDG uptake in brown fat. The differences in SUVmax between the two scans ranged from -20 percent to +20 percent. Based on our observation, dual time point imaging may not be a reliable method for assessing the 18F-FDG uptake of brown fat.