Ketamine-xylazine/tiletamine-zolazepam prolonged anesthesia in Cynomolgus monkeys

• Main Authors: Cheah, Pike See, Low, Kiat Cheong, Mohidin, Norhani, Mohd Ali, Bariah, Myint, Maung, Abdul Latiff, Azian
• Format: Article
• Language: English
• Published: Online Journal of Veterinary Research 2007
• Online Access: http://psasir.upm.edu.my/id/eprint/15383/1/Ketamine-xylazine%20tiletamine-zolazepam.pdf; http://psasir.upm.edu.my/id/eprint/15383/; http://onljvetres.com/ketaminemonkeysabs2007.htm
• Institution: Universiti Putra Malaysia

The physiological effects of a mixture of ketamine, xylazine, tiletamine and zolazepam (KT/XZ), in cynomolgus monkeys during 24 hr anesthesia is described. Eight were induced with ketamine IM and anesthetized with IV KT/XZ. In all, anesthesia was maintained for 24 hours with large decreases in rectal temperature, heart and respiratory rates but moderate hypotension. All monkeys recovered normally 4 hours post-anesthesia. These results suggest that KX/TZ mixture could be used for prolonged anesthesia in cynomolgus monkeys.