Naturally occurring labdane diterpene and benzofuran from Globba pendula.

Naturally occurring labdane diterpene and benzofuran from Globba pendula.

Phytochemical investigation on Globba pendula resulted in the isolation of a new naturally occurring 16-oxo-(8)17-12-labdadien-15,11-olide 1 and benzofuran-2-carboxaldehyde 2. Other known compounds including isoandrographolide, indirubin, vanillin, vanillic acid, 2(3H)-benzoxazolone, as well as beta...

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Main Authors: Maulidiani, H.M, Shaari , Khozirah, Paetz , ChristiaN, Stanslas, Johnson, Abas, Faridah, Lajis, Nordin
Format: Article
Language:English
Published: Natural Product Communications 2009
Online Access:http://psasir.upm.edu.my/id/eprint/15783/
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Institution: Universiti Putra Malaysia
Language: English
id my.upm.eprints.15783
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spelling my.upm.eprints.157832013-05-22T03:21:14Z http://psasir.upm.edu.my/id/eprint/15783/ Naturally occurring labdane diterpene and benzofuran from Globba pendula. Maulidiani, H.M Shaari , Khozirah Paetz , ChristiaN Stanslas, Johnson Abas, Faridah Lajis, Nordin Phytochemical investigation on Globba pendula resulted in the isolation of a new naturally occurring 16-oxo-(8)17-12-labdadien-15,11-olide 1 and benzofuran-2-carboxaldehyde 2. Other known compounds including isoandrographolide, indirubin, vanillin, vanillic acid, 2(3H)-benzoxazolone, as well as beta-sitosteryl-beta-D-glucopyranoside, beta-sitosterol, and 7alpha-hydroxysitosterol were also isolated. The structures were established based on spectroscopic data and comparison with the literature. Furthermore, the compound isoandrographolide has demonstrated strong cytotoxic properties towards a panel of cancer cell lines (MCF-7, PC-3, and H-460) with the IC50 values of 7.9, 8.7, and 9.0 microM, respectively. Natural Product Communications 2009 Article PeerReviewed Maulidiani, H.M and Shaari , Khozirah and Paetz , ChristiaN and Stanslas, Johnson and Abas, Faridah and Lajis, Nordin (2009) Naturally occurring labdane diterpene and benzofuran from Globba pendula. Natural Product Communications, 4 (8). pp. 1031-1036. ISSN 1934-578X English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Phytochemical investigation on Globba pendula resulted in the isolation of a new naturally occurring 16-oxo-(8)17-12-labdadien-15,11-olide 1 and benzofuran-2-carboxaldehyde 2. Other known compounds including isoandrographolide, indirubin, vanillin, vanillic acid, 2(3H)-benzoxazolone, as well as beta-sitosteryl-beta-D-glucopyranoside, beta-sitosterol, and 7alpha-hydroxysitosterol were also isolated. The structures were established based on spectroscopic data and comparison with the literature. Furthermore, the compound isoandrographolide has demonstrated strong cytotoxic properties towards a panel of cancer cell lines (MCF-7, PC-3, and H-460) with the IC50 values of 7.9, 8.7, and 9.0 microM, respectively.
format Article
author Maulidiani, H.M
Shaari , Khozirah
Paetz , ChristiaN
Stanslas, Johnson
Abas, Faridah
Lajis, Nordin
spellingShingle Maulidiani, H.M
Shaari , Khozirah
Paetz , ChristiaN
Stanslas, Johnson
Abas, Faridah
Lajis, Nordin
Naturally occurring labdane diterpene and benzofuran from Globba pendula.
author_facet Maulidiani, H.M
Shaari , Khozirah
Paetz , ChristiaN
Stanslas, Johnson
Abas, Faridah
Lajis, Nordin
author_sort Maulidiani, H.M
title Naturally occurring labdane diterpene and benzofuran from Globba pendula.
title_short Naturally occurring labdane diterpene and benzofuran from Globba pendula.
title_full Naturally occurring labdane diterpene and benzofuran from Globba pendula.
title_fullStr Naturally occurring labdane diterpene and benzofuran from Globba pendula.
title_full_unstemmed Naturally occurring labdane diterpene and benzofuran from Globba pendula.
title_sort naturally occurring labdane diterpene and benzofuran from globba pendula.
publisher Natural Product Communications
publishDate 2009
url http://psasir.upm.edu.my/id/eprint/15783/
_version_ 1643826028765773824

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