Preparation, characterization, and in ovo vaccination of dextran-spermine nanoparticle DNA vaccine coexpressing the fusion and hemagglutinin genes against Newcastle disease

• Main Authors: Firouzamandi, Masoumeh, Moeini, Hassan, Hosseini, Seyed Davood, Bejo, Mohd Hair, Omar, Abdul Rahman, Mehrbod, Parvaneh, El Zowalaty, Mohamed E., Webster, Thomas J., Ideris, Aini
• Format: Article
• Language: English
• Published: Dove Medical Press 2016
• Online Access: http://psasir.upm.edu.my/id/eprint/16992/1/16992.pdf; http://psasir.upm.edu.my/id/eprint/16992/; https://www.dovepress.com/preparation-characterization-and-in-ovo-vaccination-of-dextran-spermin-peer-reviewed-article-IJN
• Institution: Universiti Putra Malaysia

Plasmid DNA (pDNA)-based vaccines have emerged as effective subunit vaccines against viral and bacterial pathogens. In this study, a DNA vaccine, namely plasmid internal ribosome entry site-HN/F, was applied in ovo against Newcastle disease (ND). Vaccination was carried out using the DNA vaccine alo...