Display of the antigenic region of Nipah virus nucleocapsid protein on hepatitis B virus capsid

The C-terminal domain of Nipah virus (NiV) nucleocapsid protein (NP 401-532) was inserted at the N-terminus and the immunodominant loop of hepatitis B core antigen (HBc). The stability of NP 401-532 increased tremendously when displayed on the HBc particles. These particles reacted specifically with...

Full description

Saved in:
Bibliographic Details
Main Authors: Yap, Wei Boon, Tey, Beng Ti, Mohammed Alitheen, Noorjahan Banu, Tan, Wen Siang
Format: Article
Language:English
Published: The Society for Biotechnology, Japan 2012
Online Access:http://psasir.upm.edu.my/id/eprint/24187/1/Display%20of%20the%20antigenic%20region%20of%20Nipah%20virus%20nucleocapsid%20protein%20on%20hepatitis%20B%20virus%20capsid.pdf
http://psasir.upm.edu.my/id/eprint/24187/
http://www.sciencedirect.com/science/article/pii/S138917231100380X
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Universiti Putra Malaysia
Language: English
Description
Summary:The C-terminal domain of Nipah virus (NiV) nucleocapsid protein (NP 401-532) was inserted at the N-terminus and the immunodominant loop of hepatitis B core antigen (HBc). The stability of NP 401-532 increased tremendously when displayed on the HBc particles. These particles reacted specifically with the swine anti-NiV and the human anti-HBc antisera.