Prenatal screening of down syndrome.
The present invention provides a method using polymerasa chain reaction (PCR) for detecting Down syndrom in the fetus of a pregnant woman by way of determining the increased concentration levels of supeoxide dismutase-1 (SOD-1) gene sequence in maternal extra-cellular body fluid. Accordingly, the pr...
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| Main Authors: | , |
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| Format: | Patent |
| Published: |
2006
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| Online Access: | http://psasir.upm.edu.my/id/eprint/25874/ |
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| Institution: | Universiti Putra Malaysia |
| Summary: | The present invention provides a method using polymerasa chain reaction (PCR) for detecting Down syndrom in the fetus of a pregnant woman by way of determining the increased concentration levels of supeoxide dismutase-1 (SOD-1) gene sequence in maternal extra-cellular body fluid. Accordingly, the present invention provides a method for screening Down syndrom fetus using DNA aplification promers and gene specific probe for specifically amplifying and quantifying superoxide dismutase-1 (SOD-1) gene in a pregnant woman. The invention also relates to a diagnostic kit for carrying out the invention method.
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