Heterogeneity of Mouse Macrophages in Terms of Their Bactericidal Activity

These studies confirm that not all cells in a macrophage population express efective bactericidal functions. Two subsets of macrophages with cell-surface markers recognized by two monoclonal antibodies, designated M43 and 1\157 were shown to be involved in the bacteicidal activity of a macrophage...

Full description

Saved in:
Bibliographic Details
Main Authors: Musa, M, Rowley, D.
Format: Article
Language:English
English
Published: 1990
Online Access:http://psasir.upm.edu.my/id/eprint/2837/1/Heterogeneity_of_Mouse_Macrophages_in_Terms_of.pdf
http://psasir.upm.edu.my/id/eprint/2837/
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Universiti Putra Malaysia
Language: English
English
Description
Summary:These studies confirm that not all cells in a macrophage population express efective bactericidal functions. Two subsets of macrophages with cell-surface markers recognized by two monoclonal antibodies, designated M43 and 1\157 were shown to be involved in the bacteicidal activity of a macrophage population. B)' indirect radio immunoassay (RIA), it was found that these two subset markers were expressed more on the 5tu/ace of activated manipulates than on normal cells. It seems possible that these two markers may se11Je as markers for macrophage activation in terms of enhanced bactericidal activity.