Suppression of cancer-initiating cells and selection of adipose-derived stem cells cultured on biomaterials having specific nanosegments

• Main Authors: Kao, Ta Chun, Lee, Henry Hsin Chung, Higuchi, Akon, Ling, Qing Dong, Yu, Wan Chun, Chou, Yu Hsuan, Wang, Pin Yu, Kumar, S. Suresh, Chang, Yu, Chen, Yung Hung, Chang, Yung, Chen, Da Chung, Hsu, Shih Tien
• Format: Article
• Published: Wiley 2014
• Online Access: http://psasir.upm.edu.my/id/eprint/35537/; http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33024/abstract
• Institution: Universiti Putra Malaysia

Cancer-initiating cells [cancer stem cells (CSCs)] in colon cancer cells can be selectively suppressed when they are cultured on Pluronic (nanosegment)-grafted dishes, whereas CSCs are maintained on conventional tissue culture dishes and extracellular matrix-coated dishes. CSCs persist in tumors as...