Synthesis, characterization, controlled release and cytotoxic effect of anthranilic acid-loaded chitosan and polyethylene glycol-magnetic nanoparticles on murine macrophage raw 264.7 cells

• Main Authors: Al Ali, Samer Hasan Hussein, Arulselvan, Palanisamy, Hussein, Mohd. Zobir, Fakurazi, Sharida, Ismail, Maznah, Dorniani, Dena, El Zowalaty, Mohammad Ezzat
• Format: Article
• Language: English
• Published: World Scientific Publishing 2014
• Online Access: http://psasir.upm.edu.my/id/eprint/35584/1/35584.pdf; http://psasir.upm.edu.my/id/eprint/35584/; http://www.worldscientific.com/doi/abs/10.1142/S1793292014500167
• Institution: Universiti Putra Malaysia

Magnetic nanoparticles (MNPs) were prepared by the coprecipitation method using a molar ratio of Fe3+:Fe2+ of 2:1. The surface of MNP was coated with chitosan (CS) and polyethylene glycol (PEG) to form CS–MNP and PEG–MNP nanoparticles, respectively. Anthranilic acid (AA) was loaded on the surface of...