Transgene expression from CpG-reduced lentiviral gene delivery vectors in vitro

Current viral gene delivery vectors for gene therapy are inefficient due to short-lived transgene expression attributed to the cytosine-phosphate-guanine (CpG) motifs in the transgene. Here we assessed the effects of CpG motif reduction in lentiviral (LV) gene delivery context on the level and durat...

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Bibliographic Details
Main Authors: Low, Poh Tee, Lai, Mei I., Ngai, Siew Ching, Abdullah, Syahrilnizam
Format: Article
Published: Elsevier 2014
Online Access:http://psasir.upm.edu.my/id/eprint/35891/
http://www.sciencedirect.com/science/article/pii/S037811191301295X
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Institution: Universiti Putra Malaysia