Identification of anti-proliferative kinase inhibitors as potential therapeutic agents to treat canine osteosarcoma

• Main Authors: Mauchle, Ulrike, Selvarajah, Gayathri Thevi, Mol, Jan A., Kirpensteijn, Jolle, Verheije, Monique H.
• Format: Article
• Language: English
• Published: Elsevier 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/37916/1/Identification%20of%20anti-proliferative%20kinase%20inhibitors%20as%20potential%20therapeutic%20agents%20to%20treat%20canine%20osteosarcoma.pdf; http://psasir.upm.edu.my/id/eprint/37916/; http://www.sciencedirect.com/science/article/pii/S109002331400327X
• Institution: Universiti Putra Malaysia

Osteosarcoma is the most common primary bone tumour in dogs but various forms of therapy have not significantly improved clinical outcomes. As dysregulation of kinase activity is often present in tumours, kinases represent attractive molecular targets for cancer therapy. The purpose of this study wa...