Mutagenic study of benzimidazole derivatives with (+S9) and without (−S9) metabolic activation

• Main Authors: Azahar, Nurul Hafizan, Ab Dullah, Siti Soleha, Abdullah, Rozaini, Ahmat, Norizan, Md. Akim, Abdah, Ab. Hamid, Hasiah
• Format: Article
• Language: English
• Published: MDPI 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/38267/1/38267.pdf; http://psasir.upm.edu.my/id/eprint/38267/; https://www.mdpi.com/1422-0067/20/18/4324
• Institution: Universiti Putra Malaysia

Benzimidazole derivatives have a diverse range of biological activities, including antiulcer, antihypertensive, antiviral, antifungal, anti-inflammatory, and anticancer. Despite these activities, previous studies have revealed that some of the derivatives can induce mutations. This study aimed to sc...