Targeting of CD133+ cancer stem cells by mesenchymal stem cell expressing TRAIL reveals a prospective role of apoptotic gene regulation in non-small cell lung cancer

• Main Authors: Shaik M. Fakiruddin, Shaik Ahmad Kamal, Lim, Moon Nian, Nordin, Norshariza, Rosli, Rozita, Zakaria, Zubaidah, Abdullah, Syahrilnizam
• Format: Article
• Language: English
• Published: MDPI 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/38282/1/38282.pdf; http://psasir.upm.edu.my/id/eprint/38282/; https://www.mdpi.com/2072-6694/11/9/1261
• Institution: Universiti Putra Malaysia

Mesenchymal stem cells (MSCs) are emerging as vehicles for anti-tumor cytotherapy; however, investigation on its efficacy to target a specific cancer stem cell (CSC) population in non-small cell lung cancer (NSCLC) is lacking. Using assays to evaluate cell proliferation, apoptosis, and gene expressi...