Polyhydroxy surfactants for the formulation of lipid nanoparticles (SLN and NLC): effects on size, physical stability and particle matrix structure

• Main Authors: Kovacevic, Andjelka, Savic, Snezana D., Vuleta, Gordana, Muller, Rainer Helmut, Keck, Cornelia M.
• Format: Article
• Language: English
• Published: Elsevier 2011
• Online Access: http://psasir.upm.edu.my/id/eprint/40320/1/Polyhydroxy%20surfactants%20for%20the%20formulation%20of%20lipid%20nanoparticles%20%28SLN%20and%20NLC%29%20effects%20on%20size%2C%20physical%20stability%20and%20particle%20matrix%20structure.pdf; http://psasir.upm.edu.my/id/eprint/40320/; http://www.sciencedirect.com/science/article/pii/S0378517311000081
• Institution: Universiti Putra Malaysia

The two polyhydroxy surfactants polyglycerol 6-distearate (Plurol®Stearique WL1009 – (PS)) and caprylyl/capryl glucoside (Plantacare® 810 – (PL)) are a class of PEG-free stabilizers, made from renewable resources. They were investigated for stabilization of aqueous solid lipid nanoparticle (SLN) and...