The synthetic curcuminoid BHMC restores endotoxin-stimulated HUVEC dysfunction: specific disruption on enzymatic activity of p38 MAPK

• Main Authors: Chau, Ling Tham, Harith, Hanis Hazeera, Kok, Wai Lam, Yi, Joong Chong, Cheema, Manraj Singh, Sulaiman, Mohd Roslan, Lajis, Nordin, Ahmad Israf, Daud
• Format: Article
• Language: English
• Published: Elsevier 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/46706/1/The%20synthetic%20curcuminoid%20BHMC%20restores%20endotoxin-stimulated%20HUVEC%20dysfunction%20specific%20disruption%20on%20enzymatic%20activity%20of%20p38%20MAPK.pdf; http://psasir.upm.edu.my/id/eprint/46706/; http://www.elsevier.com/locate/issn/00142999
• Institution: Universiti Putra Malaysia

2,6-bis-(4-hydroxyl-3-methoxybenzylidine)cyclohexanone (BHMC) has been proven to selectively inhibit the synthesis of proinflammatory mediators in lipopolysaccharide-induced U937 monocytes through specific interruption of p38 Mitogen-Activated Protein Kinase enzymatic activity and improves the survi...