Heterologous expression and characterization of L-asparaginase from marine Photobacterium sp. strain J15

• Main Author: Yaacob, Mohd Adilin
• Format: Thesis
• Language: English
• Published: 2014
• Subjects: Gene expression; Catalyts; Escherichia coli
• Online Access: http://psasir.upm.edu.my/id/eprint/52004/1/FBSB%202014%2021.pdf; http://psasir.upm.edu.my/id/eprint/52004/
• Institution: Universiti Putra Malaysia

L-asparaginase catalyzes the conversion of the L-asparagine to L-aspartate and ammonia. Although L-asparaginase is one of the main components used in chemotherapy, toxicity problem associated with glutaminase activity of commercial asparaginase products such as Elspar, oncaspar and Erwinaze derived...