Prediction of optimum compositions of parenteral nanoemulsion system loaded with low solubility drug for treatment of schizophrenia by artificial neural network

• Main Authors: Samiun, Wan Sarah, Basri, Mahiran, Masoumi, Hamid Reza Fard, Khairudin, Nurshafira
• Format: Article
• Language: English
• Published: Royal Society of Chemistry 2016
• Online Access: http://psasir.upm.edu.my/id/eprint/53635/1/Prediction%20of%20optimum%20compositions%20of%20parenteral%20.pdf; http://psasir.upm.edu.my/id/eprint/53635/
• Institution: Universiti Putra Malaysia

Aripiprazole was encapsulated in the palm kernel oil esters nanoemulsion for the purpose of brain delivery via intravenous administration. High shear and high pressure homogenizers were applied for formulating low solubility drug in the nanoemulsion system and stabilized by different emulsifiers; le...