Carbon nanotubes/pectin/minerals substituted apatite nanocomposite depositions on anodized titanium for hard tissue implant: in vivo biological performance

A surface deposition approach enveloping the use of biocompatible trace components and strengthening materials will affect the physicochemical and osseointegration properties of nanocomposite deposited implants. The current work is aimed at the development of functionalized carbon nanotubes (f-CNT)/...

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Main Authors: Govindaraj, Dharman, Rajan, Mariappan, Murugan, Alwarkurichi Munusamy, A. Alarfaj, Abdullah, Higuchi, Akon, Subbiah, Suresh Kumar
Format: Article
Language:English
Published: Elsevier 2017
Online Access:http://psasir.upm.edu.my/id/eprint/61047/1/Carbon%20nanotubespectinminerals%20substituted%20apatite%20nanocomposite%20depositions%20on%20anodized%20titanium%20for%20hard%20tissue%20implant%20in%20vivo%20biological%20performance.pdf
http://psasir.upm.edu.my/id/eprint/61047/
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Institution: Universiti Putra Malaysia
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spelling my.upm.eprints.610472019-01-29T08:00:18Z http://psasir.upm.edu.my/id/eprint/61047/ Carbon nanotubes/pectin/minerals substituted apatite nanocomposite depositions on anodized titanium for hard tissue implant: in vivo biological performance Govindaraj, Dharman Rajan, Mariappan Murugan, Alwarkurichi Munusamy A. Alarfaj, Abdullah Higuchi, Akon Subbiah, Suresh Kumar A surface deposition approach enveloping the use of biocompatible trace components and strengthening materials will affect the physicochemical and osseointegration properties of nanocomposite deposited implants. The current work is aimed at the development of functionalized carbon nanotubes (f-CNT)/Pectin (P)/mineralized hydroxyapatite (M-HA) ((f-CNT/P/M-HA)) nanocomposite depositions by electrophoretic deposition on anodized titanium (TiO2) implant. The capacity of f-CNT manages the cost of mechanical strength, while pectin (extracted from pomegranate peel) and minerals (strontium, magnesium, and zinc) enhance the biocompatibility of the HA deposition was investigate utilizing different methods. The functional and morphological analyses were done by FTIR, XRD, XPS, SEM-EDX and TEM. The mechanical depiction results show improved adherence quality for the nanocomposite deposition. Additionally, an enhanced viability of osteoblast cells (MG63 (HOS)) was monitored in vitro on the f-CNT/P/M-HA nanocomposite deposition. The capacity of the nanocomposite deposited TiO2 implant to encourage bone development was assessed in vivo. Hence, the as-synthesized nanocomposite deposited TiO2 that joins the comfort osteoconductivity of mineralized hydroxyapatite, pectin collectively with the compressive strength of f-CNT can have numerous uses in orthopaedics since it could enhance implant fixation in human bone. Elsevier 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/61047/1/Carbon%20nanotubespectinminerals%20substituted%20apatite%20nanocomposite%20depositions%20on%20anodized%20titanium%20for%20hard%20tissue%20implant%20in%20vivo%20biological%20performance.pdf Govindaraj, Dharman and Rajan, Mariappan and Murugan, Alwarkurichi Munusamy and A. Alarfaj, Abdullah and Higuchi, Akon and Subbiah, Suresh Kumar (2017) Carbon nanotubes/pectin/minerals substituted apatite nanocomposite depositions on anodized titanium for hard tissue implant: in vivo biological performance. Materials Chemistry and Physics, 194. 77 - 89. ISSN 0254-0584; ESSN: 1879-3312 10.1016/j.matchemphys.2017.03.039
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description A surface deposition approach enveloping the use of biocompatible trace components and strengthening materials will affect the physicochemical and osseointegration properties of nanocomposite deposited implants. The current work is aimed at the development of functionalized carbon nanotubes (f-CNT)/Pectin (P)/mineralized hydroxyapatite (M-HA) ((f-CNT/P/M-HA)) nanocomposite depositions by electrophoretic deposition on anodized titanium (TiO2) implant. The capacity of f-CNT manages the cost of mechanical strength, while pectin (extracted from pomegranate peel) and minerals (strontium, magnesium, and zinc) enhance the biocompatibility of the HA deposition was investigate utilizing different methods. The functional and morphological analyses were done by FTIR, XRD, XPS, SEM-EDX and TEM. The mechanical depiction results show improved adherence quality for the nanocomposite deposition. Additionally, an enhanced viability of osteoblast cells (MG63 (HOS)) was monitored in vitro on the f-CNT/P/M-HA nanocomposite deposition. The capacity of the nanocomposite deposited TiO2 implant to encourage bone development was assessed in vivo. Hence, the as-synthesized nanocomposite deposited TiO2 that joins the comfort osteoconductivity of mineralized hydroxyapatite, pectin collectively with the compressive strength of f-CNT can have numerous uses in orthopaedics since it could enhance implant fixation in human bone.
format Article
author Govindaraj, Dharman
Rajan, Mariappan
Murugan, Alwarkurichi Munusamy
A. Alarfaj, Abdullah
Higuchi, Akon
Subbiah, Suresh Kumar
spellingShingle Govindaraj, Dharman
Rajan, Mariappan
Murugan, Alwarkurichi Munusamy
A. Alarfaj, Abdullah
Higuchi, Akon
Subbiah, Suresh Kumar
Carbon nanotubes/pectin/minerals substituted apatite nanocomposite depositions on anodized titanium for hard tissue implant: in vivo biological performance
author_facet Govindaraj, Dharman
Rajan, Mariappan
Murugan, Alwarkurichi Munusamy
A. Alarfaj, Abdullah
Higuchi, Akon
Subbiah, Suresh Kumar
author_sort Govindaraj, Dharman
title Carbon nanotubes/pectin/minerals substituted apatite nanocomposite depositions on anodized titanium for hard tissue implant: in vivo biological performance
title_short Carbon nanotubes/pectin/minerals substituted apatite nanocomposite depositions on anodized titanium for hard tissue implant: in vivo biological performance
title_full Carbon nanotubes/pectin/minerals substituted apatite nanocomposite depositions on anodized titanium for hard tissue implant: in vivo biological performance
title_fullStr Carbon nanotubes/pectin/minerals substituted apatite nanocomposite depositions on anodized titanium for hard tissue implant: in vivo biological performance
title_full_unstemmed Carbon nanotubes/pectin/minerals substituted apatite nanocomposite depositions on anodized titanium for hard tissue implant: in vivo biological performance
title_sort carbon nanotubes/pectin/minerals substituted apatite nanocomposite depositions on anodized titanium for hard tissue implant: in vivo biological performance
publisher Elsevier
publishDate 2017
url http://psasir.upm.edu.my/id/eprint/61047/1/Carbon%20nanotubespectinminerals%20substituted%20apatite%20nanocomposite%20depositions%20on%20anodized%20titanium%20for%20hard%20tissue%20implant%20in%20vivo%20biological%20performance.pdf
http://psasir.upm.edu.my/id/eprint/61047/
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