Improved cultivation of gdhA derivative Pasteurella multocida B: 2 for high density of viable cells through in situ ammonium removal using cation-exchange resin for use as animal vaccine

• Main Authors: Oslan, Siti Nur Hazwani, Tan, Joo Shun, Saad, Mohd Zamri, Halim, Murni, Ariff, Arbakariya
• Format: Article
• Language: English
• Published: Elsevier 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/62115/1/Improved%20cultivation%20of%20gdhA%20derivative%20Pasteurella%20multocida%20.pdf; http://psasir.upm.edu.my/id/eprint/62115/; https://www.sciencedirect.com/science/article/pii/S1359511316305839
• Institution: Universiti Putra Malaysia

Pasteurella multocida serotype B:2 is the causative agent of hemorrhagic septicemia, a fatal disease of cattle and buffaloes. A live attenuated vaccine, gdhA derivative P. multocida B:2 mutant, was created to defeat the disease. During the cultivation of P. multocida B:2 mutant, substantial amount o...