Increased loading, efficacy and sustained release of silibinin, a poorly soluble drug using hydrophobically-modified chitosan nanoparticles for enhanced delivery of anticancer drug delivery systems

Increased loading, efficacy and sustained release of silibinin, a poorly soluble drug using hydrophobically-modified chitosan nanoparticles for enhanced delivery of anticancer drug delivery systems

Conventional delivery of anticancer drugs is less effective due to pharmacological drawbacks such as lack of aqueous solubility and poor cellular accumulation. This study reports the increased drug loading, therapeutic delivery, and cellular accumulation of silibinin (SLB), a poorly water-soluble ph...

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Bibliographic Details
Main Authors: Cha, Yee Kuen, Fakurazi, Sharida, Othman, Siti Sarah, Masarudin, Mas Jaffri
Format: Article
Language:English
Published: MDPI 2017
Online Access:http://psasir.upm.edu.my/id/eprint/62145/1/Increased%20loading%2C%20efficacy%20and%20sustained%20release.pdf
http://psasir.upm.edu.my/id/eprint/62145/
https://www.mdpi.com/2079-4991/7/11/379
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Institution: Universiti Putra Malaysia
Language: English

Internet

http://psasir.upm.edu.my/id/eprint/62145/1/Increased%20loading%2C%20efficacy%20and%20sustained%20release.pdf
http://psasir.upm.edu.my/id/eprint/62145/
https://www.mdpi.com/2079-4991/7/11/379

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