Synthesis and cytotoxic effects of (E)-3-(2,3-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one in MDA-MB231 and MCF-7 breast cancer cell lines

A chalcone derivative, (E)-3-(2,3-dimethoxyphenyl)-1-(5-methylfuran-2-yl)-prop-2-en-1-one (DMMF) was synthesized and evaluated against various cancerous cell lines including colon adenocarcinoma (HT-29), myloplasticleukemia (HL60), breast cancer (MCF-7 and MDA-MB231), normal hepatic cell (WRL-68) an...

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Main Authors: Akhtar, Muhammad Nadeem, Salim, Landa Zeenelabdin Ali, Swee, Keong Yeap, Abu, Nadiah, Zareen, Seema, Kong, Mun Lo, Bakar, Addila abu, Alitheen, Noorjahan Banu
Format: Article
Language:English
Published: Elsevier 2017
Online Access:http://psasir.upm.edu.my/id/eprint/63357/1/Synthesis%20and%20cytotoxic%20effects%20of%20%28E%29-3-%282%2C3-dimethoxyphenyl%29-1-%285-methylfuran-2-yl%29%20prop-2-en-1-one%20in%20MDA-MB231%20and%20MCF-7%20breast%20cancer%20cell%20lines.pdf
http://psasir.upm.edu.my/id/eprint/63357/
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Institution: Universiti Putra Malaysia
Language: English