Expression analysis of α-TTP, PI-TP and SPF genes in H₂O₂-induced HUVECs and neuronal cells supplemented with α-tocopherol and Tocotrienol-Rich Fraction

• Main Author: Chiroma, Aishatu Ali
• Format: Thesis
• Language: English
• Published: 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/70532/1/FPSK%28M%29%202017%2046%20-%20IR.pdf; http://psasir.upm.edu.my/id/eprint/70532/
• Institution: Universiti Putra Malaysia

Vitamin E has 8 isoforms namely; α, β, γ, δ -tocopherols (TCP) and α, β, γ, δ -tocotrienols (TCT). Natural α-tocopherol (α-TCP) but not TCT is preferentially retained in the human body. Studies showed that α-tocopherol transfer protein (α-TTP) is responsible to bind α-TCP for cellular uptake. Howev...