Carcinogenic effects of n-methyl-n-nitrosourea administered via oral and intraperitoneal routes in female sprague dawley rats

• Main Author: Mohd Kassim, Muhammad Hakimi
• Format: Thesis
• Language: English
• Published: 2014
• Subjects: Cancer; Diagnosis, Noninvasive
• Online Access: http://psasir.upm.edu.my/id/eprint/70853/1/FPV%202014%2038%20-%20IR.pdf; http://psasir.upm.edu.my/id/eprint/70853/
• Institution: Universiti Putra Malaysia

N-methyl-N-nitrosourea (MNU) is able to induce multiple tumours via different routes of administration. The development of tumours is well associated with failure of apoptosis process. In cancer studies, real time quantitative reverse transcription polymerase chain reaction (qRT-PCR) is widely...