Design, synthesis and docking studies of Flavokawain B type chalcones and their cytotoxic effects on MCF-7 and MDA-MB-231 cell lines

Design, synthesis and docking studies of Flavokawain B type chalcones and their cytotoxic effects on MCF-7 and MDA-MB-231 cell lines

Flavokawain B (1) is a natural chalcone extracted from the roots of Piper methysticum, and has been proven to be a potential cytotoxic compound. Using the partial structure of flavokawain B (FKB), about 23 analogs have been synthesized. Among them, compounds 8, 13 and 23 were found in new FKB deriva...

Full description

Saved in:
Bibliographic Details
Main Authors: Abu Bakar, Addila, Akhtar, Muhammad Nadeem, Mohd Ali, Norlaily, Yeap, Swee Keong, Quah, Ching Kheng, Loh, Wan-Sin, Mohammed Alitheen, Noorjahan Banu, Zareen, Seema, Ul-Haq, Zaheer, Shah, Syed Adnan Ali
Format: Article
Language:English
Published: Multidisciplinary Digital Publishing Institute 2018
Online Access:http://psasir.upm.edu.my/id/eprint/72197/1/Design%2C%20synthesis%20and%20docking%20studies%20.pdf
http://psasir.upm.edu.my/id/eprint/72197/
https://www.mdpi.com/1420-3049/23/3/616
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Universiti Putra Malaysia
Language: English

Internet

http://psasir.upm.edu.my/id/eprint/72197/1/Design%2C%20synthesis%20and%20docking%20studies%20.pdf
http://psasir.upm.edu.my/id/eprint/72197/
https://www.mdpi.com/1420-3049/23/3/616

Similar Items