Generation of induced pluripotent stem cells by a polycistronic lentiviral vector in feeder- and serum- free defined culture

• Main Authors: Al Abbar, Akram Faisal Mahmaud, Nordin, Norshariza, Ghazalli, Nadiah, Abdullah, Syahrilnizam
• Format: Article
• Language: English
• Published: Elsevier 2018
• Online Access: http://psasir.upm.edu.my/id/eprint/72831/1/Generation%20of%20induced%20pluripotent%20stem%20cells%20.pdf; http://psasir.upm.edu.my/id/eprint/72831/; https://pubmed.ncbi.nlm.nih.gov/30503056/
• Institution: Universiti Putra Malaysia

Induced pluripotent stem cells (iPSCs) have great potentials for regenerative medicine. However, serious concerns such as the use of the viral-mediated reprogramming strategies and exposure of iPSCs to animal products from feeder cells and serum-containing medium have restricted the application of i...