Plasma alpha-1-acid glycoprotein as a potential predictive biomarker for non-haematological adverse events of docetaxel in breast cancer patients

• Main Authors: Jabir, Rafid Salim, Gwo, Fuang Ho, Ahmad Annuar, Muhammad Azrif, Stanslas, Johnson
• Format: Article
• Language: English
• Published: Taylor & Francis 2018
• Online Access: http://psasir.upm.edu.my/id/eprint/73537/1/Plasma%20alpha-1-acid%20glycoprotein%20as%20a%20potential%20predictive%20biomarker%20for%20non-haematological%20adverse%20events%20of%20docetaxel%20in%20breast%20cancer%20patients.pdf; http://psasir.upm.edu.my/id/eprint/73537/
• Institution: Universiti Putra Malaysia

Context: Rash and oral mucositis are major non-haematological adverse events (AEs) of docetaxel, in addition to fatigue, nausea, vomiting and diarrhoea, which restrict the use of the drug in cancer therapy. Alpha-1-acid glycoprotein (AAG) is an acute phase reactant glycoprotein and is a primary carr...