Impact of early postbariatric surgery acute kidney injury on long-term renal function

• Main Authors: Nor Hanipah, Zubaidah, Punchai, Suriya, Augustin, Toms, Brethauer, Stacy A., Schauer, Philip R., Aminian, Ali
• Format: Article
• Language: English
• Published: Springer 2018
• Online Access: http://psasir.upm.edu.my/id/eprint/74563/1/Impact%20of%20early%20postbariatric%20surgery%20acute%20kidney%20injury%20on%20long-term%20renal%20function.pdf; http://psasir.upm.edu.my/id/eprint/74563/; https://link.springer.com/article/10.1007%2Fs11695-018-3398-2
• Institution: Universiti Putra Malaysia

Background: Bariatric surgery can improve renal dysfunction associated with obesity and diabetes. However, acute kidney injury (AKI) can complicate the early postoperative course after bariatric surgery. The long-term consequences of early postoperative AKI on renal function are unknown. Methods: Patient undergoing bariatric surgery from 2008 to 2015 who developed AKI within 60 days after surgery were studied. Patients on dialysis before surgery were excluded. Results: Out of 4722 patients, 42 patients (0.9%) developed early postoperative AKI after bariatric surgery of whom five had chronic kidney disease (CKD) preoperatively including CKD stage 3 (n = 2), stage 4 (n = 2), and stage 5 (n = 1). Etiologies of AKI included prerenal in 37 and renal in 5 patients. Nine patients (21%) underwent hemodialysis in early postoperative period for AKI. The median duration of follow-up was 28 months (interquartile range, 4–59). Of the 40 patients eligible for follow-up, 36 patients (90%) returned to their baseline renal function. However, four patients (10%) had worsening of renal function at follow-up. Conclusions: The incidence of early postoperative AKI after bariatric surgery is about 1%. The most common causes of AKI after bariatric surgery are dehydration and infectious complications. In our series, 10% of patients who developed AKI in early postoperative period had worsening of renal function in long-term follow-up. In the absence of severe sepsis and severe underlying kidney dysfunction (CKD stages 4 and 5), full recovery is expected after postoperative AKI.