Inositol-6 phosphate inhibits the mTOR pathway and induces autophagy-mediated death in HT-29 colon cancer cells

• Main Authors: Pandurangan, Ashok Kumar, Ismail, Salmiah, Mohd Esa, Norhaizan, Munusamy, Murugan A.
• Format: Article
• Language: English
• Published: Termedia Publishing 2018
• Online Access: http://psasir.upm.edu.my/id/eprint/74694/1/Inositol-6%20phosphate%20inhibits%20the%20mTOR%20pathway.pdf; http://psasir.upm.edu.my/id/eprint/74694/; https://www.termedia.pl/Inositol-6-phosphate-inhibits-the-mTOR-pathway-and-induces-autophagy-mediated-death-in-HT-29-colon-cancer-cells,19,33250,0,1.html
• Institution: Universiti Putra Malaysia

Introduction: Colorectal cancer (CRC) is common, with a worldwide incidence estimated at more than 1 million cases annually. Therefore, the search for agents for CRC treatment is highly warranted. Inositol-6 phosphate (IP6) is enriched in rice bran and possesses many beneficial effects. In the prese...