Overexpression of interferon alpha or beta receptors in the brain of adult Ts1Cje mouse model of Down syndrome

• Main Authors: Tan, Kai Leng, Lee, Han Chung, Ling, King Hwa, Hewitt, Chelsee A., Scott, Hamish S., Lai, Mei I., Vidyadaran, Sharmili, Cheah, Pike See
• Format: Conference or Workshop Item
• Language: English
• Published: 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/75603/1/Overexpression%20of%20interferon%20alpha%20or%20beta%20receptors%20in%20the%20brain%20of%20adult%20Ts1Cje%20mouse%20model%20of%20Down%20syndrome.pdf; http://psasir.upm.edu.my/id/eprint/75603/
• Institution: Universiti Putra Malaysia

Introduction: Down syndrome (DS) is a generic disorder with trisomy of human chromosome 21 (HSA21) and all DS patients exhibited intellectual disability. Ts1Cje mouse model of DS has partial triplication of mouse chromosome 16 (MMU16) which is homologous to HSA21. The JAK (Janus kinase) and STAT (si...