Design of novel semisynethetic metalloenzyme from thermolysin
Initial applications of biocatalysis involved the used of naturally occurring enzyme. With new challenges in green chemical reaction, biocatalyst that shed the light is metalloenzyme,which function as enzyme and contain metal that are tightly attached and always isolated with the protein[1]. In r...
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Main Authors: | , , , , , |
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Format: | Conference or Workshop Item |
Language: | English |
Published: |
BioMed Central
2007
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Online Access: | http://psasir.upm.edu.my/id/eprint/7634/1/Design%20of%20novel%20semisynethetic%20metalloenzyme%20from%20thermolysin.pdf http://psasir.upm.edu.my/id/eprint/7634/ |
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Institution: | Universiti Putra Malaysia |
Language: | English |
Summary: | Initial applications of biocatalysis involved the used of
naturally occurring enzyme. With new challenges in green
chemical reaction, biocatalyst that shed the light is metalloenzyme,which function as enzyme and contain metal
that are tightly attached and always isolated with the protein[1]. In recent years, enzyme engineering has proven to be an invaluable tool for elucidating biocatalytic mechanisms as well as producing enzymes for industrial purposes.Approaches developed for in vivo chemical
modification and in silico computational methods promise
to increase the scope and have already been used successfully to alter existing protein so that they have better stability and functionality [2]. This task might be good to address in designing a new biocatalyst with improved
properties. |
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